Saturday, December 01, 2012
WORLD AIDS DAY: Time to Help Victims of HIV Drug Studies and Resistance
We have repeatedly heard the following statements about multi-drug resistant HIV (MDR-HIV) patients in a host of meetings on treatment access and HIV research: “These patients no longer exist – they’re either dead or have responded to the latest ARVs”; “Only patients who do not adhere to their HIV regimens have MDR-HIV”; and “Our clinic cannot provide expanded access programs (EAPs) due to cost and staff restraints.” However, after surveying physicians around the country, we have found that although these patients are in a minority, they do exist and are anxiously waiting for access to viable regimens that could save their lives.
No one can deny that many patients can now suppress their HIV with effective regimens that cause fewer side effects. However, a vulnerable and often forgotten minority of people are still struggling with MDR-HIV while they anxiously await for access to life-saving regimens that would finally control their virus replication. Although some of these patients may have developed resistant HIV due to lack of adherence or other issues, many of them have been strictly following their doctor’s orders for years.
They’re often veterans of drug development research who have accumulated HIV resistance as they repeatedly joined antiretroviral (ARV) studies or traditional EAPs of a single new drug out of desperation to control their HIV viral load. As they signed up for studies that helped companies get their drugs approved by the FDA, many of these patients were exposed to suboptimal HIV regimens (namely, functional monotherapy or the addition of a single new active ARV to a failing HIV regimen). It is time to create a new paradigm to break the vicious cycle of single drug access that has failed these patients.
For those who could not attend this lecture, here are a few available online: Video Lectures Lecture Handouts
Supplementation while on Meds Apr 13, 2009 Hi I have been + for 4 years now workout regularly have built some of the muscle back that I lo...
SANGAMO BIOSCIENCES PRESENTS CLINICAL DATA DEMONSTRATING HIV RESERVOIR REDUCTION IN HIV-INFECTED SUBJECTS TREATED WITH MODIFIED IMMUNE CELLS WITH ZINC FINGER NUCLEASESSANGAMO BIOSCIENCES PRESENTS CLINICAL DATA DEMONSTRATING HIV RESERVOIR REDUCTION IN HIV-INFECTED SUBJECTS TREATED WITH ZFP THERAPEUTIC®,...
By Warren Tong December 5, 2012 Introduction What new HIV medications do we have to look forward to over the next few years?...
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AIDS: 12 April 2002 - Volume 16 - Issue 6 - pp 934-937 Research Letters Sexual hormones in HIV-infected patients: the influenc...
Timing and T-Cells: The Evolution of When to Start Treatment Through One Doctor's Eyes - TheBodyPRO.comhttp://www.thebodypro.com/content/71010/timing-and-t-cells-the-evolution-of-when-to-start-.html?ic=700100 Regards, Nelson Sent f...
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