There is a direct relation between economic development and mortality. Haiti has the highest mortality rate in the americas and argentina, the us and canada have the lowest.
Head, esophagus, anal lung and bladder cancers have increased in poz patients
Factors involved are immune defficiency, inflammation, pro coagulation effect, drug toxicities, smoking, lifestyle, and family history
Increased in Il6 and D dimer seem to be related to increased heart disease in the SMART study.



